Investigation of genome instability in patients with non-alcoholic steatohepatitis

Determinants of endothelial dysfunction in patients with non-alcoholic steatohepatitis

We thank Balta et al. for their comments (1). In our study we investigated the presence of endothelial dysfunction and potential predictors of endothelial dysfunction (ED) in patients with non-alcoholic steatohepatitis (NASH) (2). We found that serum gamma glutamyl transferase (GGT) and alanine transaminase (ALT) concentrations were predictors of ED in patients with NASH. Balta et al. mention t...

Nutritional aspects in patients with non-alcoholic steatohepatitis (NASH).

BACKGROUND AND OBJECTIVES Metabolic alterations are a common feature in patients affected by non-alcoholic steato-hepatitis (NASH). A strong correlation exists between overweight, in particular visceral fat accumulation, and prevalence of NASH, especially in men. Thus, diet-induced weight loss represents a fundamental tool in disease management of these patients. The aim of the present study wa...

Endothelial dysfunction in patients with non-alcoholic steatohepatitis

Dear Editor, I read with great interest the paper by Arinc et al. (1). They investigated the presence of endothelial dysfunction in a group of patients with non-alcoholic steatohepatitis (NASH). They found that patients with NASH have impaired flow-mediated dilatation (FMD) and increased carotid artery intima-media thickness (CIMT) when compared with healthy controls. And serum concentrations o...

Non-alcoholic steatohepatitis

Non-alcoholic steatohepatitis in children.

Non-alcoholic steatohepatitis (NASH) is an important liver disease in children; it can cause cirrhosis in children. The disease mechanism involves hepatic insulin resistance with hyperinsulinemia and changes in certain adipocytokines and inflammatory mediators. The differential diagnosis of childhood NASH includes metabolic disorders, drug hepatotoxicity, and alcoholic hepatitis in adolescent p...